System Requirements
Gpg4win runs on Windows versions 7 or newer (including Windows 11). Both 32 and 64bit systems are supported. If you have at least Windows XP, some parts of Gpg4win can be used, but are not officially supported.
The Outlook add-in GpgOL is compatible with Microsoft Outlook 2010, 2013, 2016, 2019, Office 365 and 2021 (both 32 and 64bit) and supports transporting emails via SMTP/IMAP and MS Exchange Server.
The new Outlook version identifying itself as „Outlook (new)“ is actually a web-client for outlook.com and MS-365 and currently not supported by Gpg4win due to the removal of the Add-In interface. An entirely new extension to use these online versions is currently in the works and will be available as part of Gpg4win-5.
Other Systems
With MacOS X you can use the GPG Suite.
With a GNU/Linux based systems you can use the package manager to install GnuPG. Alternatively you can compile GnuPG directly from the sources by yourself.